We’ve only got 1 of these Biomedical Scientist pins left! 👩🏽🔬👨🏼🔬
CÉLULA ANIMAL .
•Núcleo Celular: estrutura esférica onde se encontra o DNA.
•Nucléolo: estrutura presente no núcleo das células. Coordena os processos de reprodução celular através da síntese de proteínas.
•Membrana Plasmática: estrutura celular fina que delimita a célula sendo responsável pela saída e entrada de sustâncias. Assim, ela tem a função de proteger as estruturas celulares internas.
•Citoplasma: região mais volumosa, onde se encontram o núcleo e as organelas celulares.
•Ribossomos: estrutura responsável pela produção e síntese de proteínas.
•Retículo Endoplasmático Liso e Rugoso: responsáveis pelo transporte de proteínas e a síntese de moléculas orgânicas.
•Complexo de Golgi: armazena, modifica e libera substâncias. Exporta proteínas sintetizadas no retículo endoplasmático rugoso e, além disso, origina os lisossomos.
•Lisossomos: estruturas responsáveis pela digestão celular.
•Mitocôndrias: estrutura responsável pela respiração celular e a produção de energia.
•Centríolos: estrutura celular que auxilia na divisão celular (mitose e meiose). Peroxissomos: estrutura arredondada responsável pelo armazenamento de enzimas.
•Vacúolos: responsáveis pela reserva energética e o armazenamento de substâncias
Fonte: Toda matéria
One year after the birth of the world’s first two cloned primates, a team in China has used CRISPR gene editing and cloning to create monkeys that show some symptoms of depression and schizophrenia.
While some researchers have praised the work’s potential for helping us understand psychiatric disorders in humans, others have raised ethical concerns.
Lead scientist Hung-Chun Chang of the Institute of Neuroscience in Shanghai told New Scientist about how he hopes the monkeys will help us better understand mental health and find new treatments.
What symptoms do these monkeys have?
The most direct result is that they are not getting enough sleep. Healthy monkeys usually sleep for 9 hours every night, but these monkeys can’t rest for longer than 6 hours.
They are also afraid of people, which is very unusual for such a sociable animal, and they show no interest in new environments.
We also found they have persistently high cortisol levels in blood tests. Elevated cortisol has been linked to anxiety and depression in monkeys and humans in past research.
Previous studies have shown that people with schizophrenia are less able to detect and pay attention to new stimuli, including sounds. We found that these monkeys have lower levels of brain activity compared with healthy monkeys when unexpected sounds were played.
What are you hoping to learn from this work?
We will use these monkeys for drug testing. We have three general goals. First, we are curious whether drugs for body clock regulation, such as sleeping pills, are helpful in alleviating depression.
Second, we want to know how effective the medicines we use currently for mental health conditions are. Ultimately, we aim to create better treatments for people.
What else is your team working on?
We are trying to create an Alzheimer’s model. Because the disease is age-related and involves more-complex genetic mutations, it will probably take another two to three years until the monkeys show symptoms.
[credit: Yvaine Ye, New Scientist]🌐
Synthego today announced its inaugural Genome Engineer Innovation Grant, which will provide $1 million worth of CRISPR tools to select research labs.
It’s part of the company’s ongoing mission to make genome engineering tools accessible to all scientists, even those with limited resources and tight budgets.
“We’re trying to drive the creation of innovative ideas,” Synthego CSO Rich Stoner told me. Big research impacts often require access to big amounts of money, tools and services. This program aims to eliminate those barriers to see what innovators can do.
“We anticipate many applications will come from researchers just starting CRISPR” and those without the means to build a CRISPR capability in their own labs, he said.
[credit: Kevin Costa, SynBioBeta]🌐